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| Scientific Programme Detail |
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Sunday, 8 July 2007
| Thrombotic disorders |
Plenary Hall |
Venous tromboembolism risk factors and prophylaxis |
Chairpersons: O. Dahl (DK), P. Kyrle (AT) |
Controversial issues regarding thromboprophylaxis in surgical patients |
Ola Dahl (UK) |
08:00 - 08:30 |
Prophylaxis in medical patients: how and for whom? |
Patrick Mismetti (FR) |
08:30 - 09:00 |
Obesity, metabolic syndrome and venous tromboembolism |
Marie-Christine Alessi (FR) |
09:00 - 09:30 |
| Haemorrhagic disorders |
Room A/B |
Controversies in haemophilia treatment |
Chairpersons: P. Lollar (US), C. Négrier (FR) |
Gene transfer for inherited bleeding disorders |
Katherine High (US) |
08:00 - 08:30 |
Improved therapeutic agents for haemophilia |
|
Pete Lollar (US) |
08:30 - 09:00 |
Plasma-derived versus recombinant products
for haemophilia treatment?
Jenny Goudemand (FR) |
09:00 - 09:30 |
| Thrombotic disorders |
Room C |
Methodological issues: study design and drug safety |
Chairpersons: A. Leizorovicz (FR), B. L. Davidson (US) |
Study design, level of evidence and guidelines
|
| Holger J. Schuenemann (IT) |
08:00 - 08:30 |
| Risk management in the development of new antithrombotic drugs |
|
Alain Leizorovicz (FR)
|
08:30 - 09:00 |
| Low-molecular-weight heparin in the elderly with impaired renal function |
|
Wendy Lim (CA) |
09:00 - 09:30 |
| Fibronolysis and fibrinogen |
Room D |
The fibrinolytic system and cell surface proteolysis |
Chairpersons: F. Blasi (IT), B. Binder (AT) |
Annexin II and fibrinolysis
|
| Katherine Hajjar (US) |
08:00 - 08:30 |
| Cell biology of the u-PA receptor |
|
Francesco Blasi (IT)
|
08:30 - 09:00 |
| Structure of u-PA / u-PA receptor complex |
|
| Mingdong Huang (CN) |
09:00 - 09:30 |
| Coagulation factors and inhibitors |
Room Cervin |
New Roles for old coagulation factors |
Chairpersons: K. T. Preissner (DE), M. M. Levi (NL) |
Novel functions of protein S |
| Tilman Hackeng (NL) |
08:00 - 08:30 |
| Role of Factor XII in thrombosis and inflammation |
|
Thomas Renné (DE)
|
08:30 - 09:00 |
| Factor VII activating protease (FSAP) |
|
| Klaus T. Preissner (DE) |
09:00 - 09:30 |
| Platelets |
Room Mont Blanc |
Platelet-pathogen interactions |
Chairpersons: E. Cramer-Bordé (FR), B. E. Kehrel (DE) |
Platelets and bacteria
|
| Dermot Cox (IE) |
08:00 - 08:30 |
| Platelets and viruses |
|
| Elisabeth Cramer-Bordé (FR) |
08:30 - 09:00 |
| Platelets and innate immunity |
|
| John Freedman (CA) |
09:00 - 09:30 |
| Vascular biology |
Room Salève |
Endothelial precursor cells |
Chairpersons: F. Dignat-George (FR), A. D. Blann (UK) |
Haematopoietic stem cells localization in the embryonic vessel wall
|
| Elaine Dzierzak (NL) |
08:00 - 08:30 |
| Endothelial progenitors and circulating endothelial cells: regeneration versus degeneration |
| Françoise Dignat-George (FR) |
08:30 - 09:00 |
| Circulating endothelial progenitors in ischemic heart |
|
| Douglas Losordo (US) |
09:00 - 09:30 |
| Haemorrhagic disorders |
Room Jura |
Haemostasis and surgery |
Chairpersons: C.M. Samama (FR), W. Korte (CH) |
Antithrombotic therapy and surgery
|
| Charles Marc Samama (FR) |
08:00 - 08:30 |
| Massive transfusion and coagulopathy:
pathophysiology and management |
| Yves Ozier (FR) |
08:30 - 09:00 |
| Treatment of life threatening bleeding |
|
| Donat Spahn (CH) |
09:00 - 09:30 |
| Plenary Lectures |
12:00 - 13:00 |
The Marion J. Barnhart Memorial Lecture |
Chairpersons: D. Meyer (FR), K. J. Clemetson (CH) |
From megakaryocytes to the platelet
|
| John Hartwig (US) |
12:00 - 12:30 |
| Haemorrhagic disorders |
Plenary Hall |
The Kenneth M. Brinkhous Memorial Lecture (Endowed by Wyeth) |
Chairpersons: G. C. White (US), P. de Moerloose (CH) |
Von Willebrand disease type 1
|
| Ian Peake (UK) |
12:30 - 13:00 |
| State-of-the-Art -Lectures |
14:15 - 15:15 |
| Thrombotic disorders |
Plenary Hall |
Chairpersons: R. Verhaeghe (BE), D. Hayoz (CH) |
Drug-eluting stents: trading thrombosis for restenosis?
|
| Eric van Belle (FR) |
14:15 - 14:45 |
Chairpersons: M. M. Samama (FR), A. S. Gallus (AU)
|
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| Past and future of genetic research in thrombosis |
|
| Pieter H. Reitsma (NL) |
14:45 - 15:15 |
| Haemorrhagic disorders |
Room A/B |
Chairpersons: H. Weiss (US), C. Balduini (IT) |
Approach to the diagnosis and management of mild bleeding disorders
|
| Michael Greaves (UK) |
14:15 - 14:45 |
| Chairpersons: W. Ageno (IT), A. Batorova (SK) |
|
| How to estimate bleeding risk in mild bleeding disorders? |
Francesco Rodeghiero (IT) |
14:45 - 15:15 |
| Coagulation factors and inhibitors |
Room C |
The Pia Glas - Greenwalt Memorial Lecture |
Chairpersons: N. A. Booth (UK), W. Ruf (US) |
Activated Protein C
|
| John Griffin (US) |
14:15 - 14:45 |
| Chairpersons: P. E. Bock (US), M. C. Guillin (FR) |
|
| Thrombin allostery |
Enrico Di Cera (US)
|
14:45 - 15:15 |
| Platelets |
Room Cervin / Mont Blanc |
Chairpersons: J. E. Italiano (US), C. Ward (AU) |
From stem cell to megakaryocyte |
| William Vainchenker (FR) |
14:15 - 14:45 |
| Vascular Biology |
Room Cervin / Mont Blanc |
Chairpersons: V. van Hinsbergh (NL), C. Ruegg (CH) |
Endothelial cell heterogeneity and thrombosis |
| William Aird (US) |
14:45 - 15:15 |
Monday, 9 July 2007
| Thrombotic disorders |
Plenary Hall |
Risk stratification and outcome in venous tromboembolism |
Chairpersons: S. Z. Goldhaber (US), G. C. Agnelli (IT) |
Long-term outcome after deep vein thrombosis |
Susan Kahn (CA) |
08:00 - 08:30 |
Risk stratification in acute pulmonary embolism:
how and what for? |
Samuel Z. Goldhaber (US) |
08:30 - 09:00 |
Long-term prognosis of pulmonary embolism |
Guy Meyer (FR) |
09:00 - 09:30 |
| Haemorrhagic disorders |
Room A/B |
Haemophilia inhibitors |
Chairpersons: J. M. Saint-Rémy (BE), G. Dolan (UK) |
Anti-idiotypic monoclonal antibodies for treatment of
factor VIII inhibitors |
Jean-Marie Saint-Rémy (BE) |
08:00 - 08:30 |
Genetic and environmental risk factors for FVIII inhibitor
development |
|
Jan Astermark (SE) |
08:30 - 09:00 |
Rituximab in the treatment of FVIII inhibitors Cindy Leissinger (US) |
09:00 - 09:30 |
| Haemorrhagic disorders |
Room C |
Rare bleeding disorders |
Chairpersons: A. Zivelin (IL), C. Lee (UK) |
What do we expect from the International Registry?
|
Flora Peyvandi (IT) |
08:00 - 08:30 |
Clinical phenotypes and factor VII genotype in
congenital factor VII deficiency |
|
Jean-François Schved (FR) |
08:30 - 09:00 |
Factor XI phenotype-genotype correlations
Ariella Zivelin (IL) |
09:00 - 09:30 |
| Fibronolysis and fibrinogen |
Room D |
Fibrinolysis and the central nervous system |
Chairpersons: D. Lawrence (US), D. Collen (BE) |
Regulation of plasminogen activator activation in
the central nervous system
|
| Daniel Lawrence (US) |
08:00 - 08:30 |
| The role of t-PA in the nervous system |
|
Sidney Stricklandor (US) |
08:30 - 09:00 |
| Plasminogen activators and proteases in stroke |
|
| Gregory Del Zoppo (US) |
09:00 - 09:30 |
| Coagulation factors and inhibitors |
Room Cervin |
Protein C |
Chairpersons: B. Dahlbäck (SE), D. Lane (UK) |
Protein C pathway |
| Björn Dahlbäck (SE) |
08:00 - 08:30 |
| Endothelial protein C receptor |
|
Charles Esmon (US)
|
08:30 - 09:00 |
| Cellular functions of APC |
|
| Matthias Riewald (US) |
09:00 - 09:30 |
| Platelets |
Room Mont Blanc |
Platelet signaling mechanisms |
Chairpersons: S. Watson (UK), R. R. Montgomery (US) |
Contact-dependent interactions that affect thrombus
growth and stability
|
| Laurence F. Brass (US) |
08:00 - 08:30 |
| NO/cGMP and ROS regulatory pathways |
|
| Ulrich Walter (DE) |
08:30 - 09:00 |
| Novel platelet membrane receptors and signaling proteins |
|
| Steve Watson (UK) |
09:00 - 09:30 |
| Vascular biology |
Room Salève |
Models of arterial and venous thrombosis |
Chairpersons: B. C. Furie (US), G. J. Johnson (US) |
In vivo monitoring of thrombus formation
|
| Barbara C. Furie (US) |
08:00 - 08:30 |
| Platelets and leukocyte interaction with the vessel wall |
| Denisa Wagner (US) |
08:30 - 09:00 |
| Thrombomodulin - guarding the vascular endothelium |
|
| Edward M. Conway (BE) |
09:00 - 09:30 |
| Innovation and technology |
Room Jura |
New cellular imaging approaches |
Chairpersons: S. Jackson (AU), W. Ouwehand (UK) |
Visual approach to proteomics
|
| Wolfgang Baumeister (DE) |
08:00 - 08:30 |
| Structural biology of cellular machines |
| Wah Chiu (US) |
08:30 - 09:00 |
| New insights into the dynamics of platelet adhesion |
|
| Shaun Jackson (AU) |
09:00 - 09:30 |
| Plenary Lectures |
12:00 - 13:00 |
| Vascular biology |
Plenary Hall |
The Wright - Schulte Memorial Lecture |
Chairpersons: C. Ruegg (CH), F. R. Rosendaal (NL) |
Cell matrix adhesion in vascular development
|
| Richard Hynes (US) |
12:00 - 12:30 |
| Innovation and technology |
Plenary Hall |
A lecture endowed by The Désiré Collen Foundation |
Chairpersons: J. M. Freyssinet (FR), C. Chesterman (AU) |
Thrombus formation in vivo
|
| Bruce Furie (US) |
12:30 - 13:00 |
| State-of-the-Art -Lectures |
14:15 - 15:15 |
| Thrombotic disorders |
Plenary Hall |
Chairpersons: J. N. Fiessinger (FR), A. Perrier (CH) |
Venous and arterial thrombosis: is there a link?
|
| Paolo Prandoni (IT) |
14:15 - 14:45 |
Chairpersons: A. K. Kakkar (UK), C. W. Francis (US)
|
|
| Cancer and thrombosis: from the molecular mechanisms
to the clinical presentations |
|
| Harry Büller (NL) |
14:45 - 15:15 |
| Haemorrhagic disorders |
Room A/B |
Chairpersons: E. Berntorp (SE), R. d'Oiron (FR) |
Immune tolerance for Factor VIII inhibitors in
haemophilia A: current strategies and future directions
|
| Donna Di Michele (US) |
14:15 - 14:45 |
| Coagulation factors and inhibitors |
Room A/B |
Chairpersons: M. Schapira (CH), J. Rosing (NL) |
Exosites in the specificity of blood coagulation reactions
|
| Paul E. Bock (US) |
|
Chairpersons: A. Nurden (FR), D.R. Phillips (US) |
Programmed autologous cleavage of platelet receptors |
| Michael C. Berndt (AU) |
14:15 - 15:15 |
| Innovation and technology |
Room C |
Chairpersons: P. de Groot (NL), A. Greinacher (DE) |
Vascular proteomics |
| Jan Schnitzer (US) |
14:45 - 15:15 |
| Fibrinolysis and fibrinogen |
Room Cervin / Mont Blanc |
Chairpersons: O. Matsuo (JP), D.C. Rijken (NL) |
Structure of fibrin: impact on clot stability |
| John Weisel (US) |
14:15 - 14:45 |
| Vascular Biology |
Room Cervin / Mont Blanc |
Chairpersons: G. D. Lowe (UK), B. Imhof (CH) |
Plaque progression and regression in atherothrombosis |
| Juan J. Badimon (US) |
14:45 - 15:15 |
Tuesday, 10 July 2007
| Presidential Symposia |
10:00 - 13:00 |
| Thrombotic disorders |
Plenary Hall |
Chairpersons: H. Bounameaux (CH), P. M. Mannucci (IT) |
Integrated diagnostic strategy for venous
thromboembolism |
Philip S. Wells (CA) |
10:00 - 10:40 |
Distal DVT: worth diagnosing? Yes |
Sebastian Schellong (DE) |
10:40 - 11:00 |
Distal DVT: worth diagnosing? No |
Marc Righini (CH) |
11:00 - 11:20 |
| |
Chairpersons: H. Bounameaux (CH), F. Bachmann (CH) |
FXa or thrombin: is Xa a better target? |
Jack Ansell (US) |
11:20 - 11:40 |
FXa or thrombin: is thrombin a better target? |
Jeffrey Weitz (CA) |
11:40 - 12:00 |
Thrombosis and bleeding disorders outside
the Western countries |
The Duckert - Koller - Lüscher Memorial Lecture |
|
| Pier M. Mannucci (IT) |
12:00 - 12:40 |
| State-of-the-Art -Lectures |
14:15 - 15:15 |
| Thrombotic disorders |
Room A |
Chairpersons: M. H. Prins (NL), G. De Gaetano (IT) |
Combined antiplatelet and anticoagulant therapy:
clinical benefits, risks and costs
|
| John Eikelboom (CA) |
14:15 - 14:45 |
Chairpersons: J. Emmerich (FR), T. Brighton (AU)
|
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| Thrombosis in the elderly: specific issues |
|
| Frits Rosendaal (NL) |
14:45 - 15:15 |
| Haemorrhagic disorders |
Room B |
Chairpersons: H. Salem (AU), J. F. Schved (FR) |
Investigation and treatment of menorrhagia
|
| Peter Kouides (US) |
14:15 - 14:45 |
| Coagulation factors and inhibitors |
Room B |
Chairpersons: D. M. Monroe (US), P. M. Sandset (NO) |
The central role of thrombin in haemostasis
|
| David Lane (UK) |
|
Chairpersons: M. Hoylaerts (BE), C. Mannhalter (AT) |
Models to evaluate antiplatelet agents |
| Peter J. Newman (US) |
14:15 - 14:45 |
| Innovation and technology |
Room C |
Chairpersons: D. Fitzgerald (IE), U. Walter (DE) |
Platelet genomics and the risk of atherothrombosis |
| Willem Ouwehand (UK) |
14:45 - 15:15 |
| Fibrinolysis and fibrinogen |
Room Cervin / Mont Blanc |
Chairpersons: S. Lord (US), H. R. Lijnen (BE) |
Congenital disorders of fibrinogen |
| Marguerite Neerman-Arbez (CH) |
14:15 - 14:45 |
| Vascular Biology |
Room Cervin / Mont Blanc |
Chairpersons: J. H. Mc Vey (UK), D. D. Wagner (US) |
Zebrafish: from haematology to hydrology |
| Pudur Jagadeeswaran (US) |
14:45 - 15:15 |
Wednesday, 11 July 2007
| Thrombotic disorders |
Plenary Hall |
Treatment of venous tromboembolism: controversies |
Chairpersons: S. Schulman (CA), H. Décousus (FR) |
Risk stratification of venous tromboembolism recurrence |
Marc Rodger (CA) |
08:00 - 08:30 |
Optimal duration of anticoagulant treatment in patients
with venous tromboembolism |
Giancarlo Agnelli (IT) |
08:30 - 09:00 |
Treatment of antiphospholipid syndrome |
Sam Schulman (CA) |
09:00 - 09:30 |
| Haemorrhagic disorders |
Room A/B |
Current and future assays of haemostasis |
Chairpersons: M. Shima (JP), M. Greaves (UK) |
Global assay using clot waveform and thrombin generation assays |
Midori Shima (JP) |
08:00 - 08:30 |
Monitoring haemostatic response using dynamic fibrin
generation methods |
|
Benny Sorensen (DK) |
08:30 - 09:00 |
Global assays of platelet function in diagnostic testing
Catherine Hayward (CA) |
09:00 - 09:30 |
Platelet disorders: clinical aspects |
Chairpersons: A. Goodall (UK), M. Cattaneo (IT) |
Clinical approach to heparin-induced thrombocytopenia
|
| Lorenzo Alberio (CH) |
08:00 - 08:30 |
| Giant platelet syndromes |
|
| Carlo L. Balduini (IT) |
08:30 - 09:00 |
| The spectrum of the platelet response |
|
| Allison Goodall (UK) |
09:00 - 09:30 |
| Thrombotic disorders |
Room D |
Thrombosis in children |
Chairpersons: M. Manco-Johnson (US), P. Monagle (AU) |
Central venous line related thrombosis in children
|
| Marilyn Manco-Johnson (US) |
08:00 - 08:30 |
| Paediatric stroke |
|
Fenella Kirkham (UK) |
08:30 - 09:00 |
| Management of arterial and venous thrombosis
in paediatric patients |
|
Anthony Chan (CA) |
09:00 - 09:30 |
| Coagulation factors and inhibitors |
Room Cervin |
Thrombin |
Chairpersons: J. A. Huntington (UK), A. Rezaie (US) |
Non PAR receptors for thrombin
|
| Raimondo De Cristofaro (IT) |
08:00 - 08:30 |
| Thrombin is a zymogen-like enzyme |
|
James A. Huntington (UK) |
08:30 - 09:00 |
| Protease activated receptors in health and disease |
|
| Shaun Coughlin (US) |
09:00 - 09:30 |
| Platelets |
Room Mont Blanc |
Thrombotic microangiopathies and ADAMTS 13 |
Chairpersons: D. Motto (US), Y. Fujimura (JP) |
Clinical aspects of hereditary and acquired thrombotic thrombocytopenic purpura |
| Johanna Kremer Hovinga (CH) |
08:00 - 08:30 |
| RADAMTS 13 structure and function |
|
Kenji Soejima (JP) |
08:30 - 09:00 |
| Mouse model of hereditary thrombotic
thrombocytopenic purpura |
|
| David Motto (US) |
09:00 - 09:30 |
| Vascular biology |
Room Salève |
Microparticles |
Chairpersons: N. Mackman (US), A. Sturk (NL) |
Clinical significance of microparticles
|
| Ingrid Pabinger (AT) |
08:00 - 08:30 |
| Role of platelet microparticles in cancer and angiogenesis |
| David Varon (IL) |
08:30 - 09:00 |
| Tissue factor and microparticles |
|
| Nigel Mackman (US) |
09:00 - 09:30 |
| Innovation and technology |
Room Jura |
The VWF-GPIb axis |
Chairpersons: J. E. Sadler (US), J. Lopez (US) |
The VWF-GPIb axis as a therapeutic target
|
| Hans Deckmyn (BE) |
08:00 - 08:30 |
| The function of GPIb |
| Zaverio Ruggeri (US) |
08:30 - 09:00 |
| The function of Von Willebrand factor |
|
| J. Evan Sadler (US) |
09:00 - 09:30 |
| Plenary Lectures |
12:00 - 13:00 |
| Fibrinolysis and fibrinogen |
Plenary Hell |
The Sol Sherry Memorial Lecture |
Chairpersons: K. A. Bauer (US), E. K. O. Kruithof (CH) |
Fibrin and fibrinolysis in infection and host defence
|
| Jay Degen (US) |
12:00 - 12:30 |
| Coagulation factors |
Plenary Hell |
The Shirley Johnson Memorial Lecture |
Chairpersons: B. Lämmle (CH), B. C. Furie (US) |
VKORC1, the molecular target of coumarins
|
| Johannes Oldenburg (DE) |
12:30 - 13:00 |
| State-of-the-Art -Lectures |
14:15 - 15:15 |
| Thrombotic disorders |
Plenary Hall |
Chairpersons: B. Brenner (IL), J. Conard (FR) |
Thrombophilia and pregnancy complications:
causation or association?
|
| Saskia Middeldorp (NL) |
14:15 - 14:45 |
Chairpersons: P. Gaussem (FR), J.H. Beer (CH)
|
|
| Antiplatelet drug resistance: molecular mechanisms
and laboratory detection |
|
| Marco Cattaneo (IT) |
14:45 - 15:15 |
| Haemorrhagic disorders |
Room A/B |
Chairpersons: I. Peake (UK), U. Seligsohn (IL) |
Phenotype heterogeneity of severe haemophilia
|
| Marijke Van den Berg (NL) |
14:15 - 14:45 |
| Coagulation factors and inhibitors |
Room A/B |
| Chairpersons: G. A. Marbet (CH), C. T. Esmon (US) |
|
| SERPINs in haemostasis, thrombosis and fibrinolysis |
Frank C. Church (US)
|
14:45 - 15:15 |
Chairpersons: A. Gallino (CH), C. Weber (DE) |
Platelets, inflammation and atherosclerosis |
| Meinrad Gawaz (DE) |
14:15 - 14:45 |
Chairpersons: D. K. Newman (US), J. W. Heemskerk (NL) |
Platelet receptor crosstalk in collagen-induced
activation of platelets |
| Richard Farndale (UK) |
14:45 - 15:15 |
| Fibrinolysis and fibrinogen |
Room Cervin / Mont Blanc |
Chairpersons: I. Juhan-Vague (FR), D. Ginsburg (US) |
Regulation of plasminogen activation |
| Robert Medcalf (AU) |
14:15 - 14:45 |
| Vascular Biology |
Room Cervin / Mont Blanc |
Chairpersons: R. De Caterina (IT), Y. Ikeda (JP) |
Endothelial progenitor cells |
| Jeremy Pearson (UK) |
14:45 - 15:15 |
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