Scientific Programme Detail  

Sunday, 8 July 2007

Symposia
08:00 - 09:30

Thrombotic disorders
Plenary Hall

Venous tromboembolism risk factors and prophylaxis

Chairpersons: O. Dahl (DK), P. Kyrle (AT)

Controversial issues regarding thromboprophylaxis in surgical patients

Ola Dahl (UK)

08:00 - 08:30

Prophylaxis in medical patients: how and for whom?

Patrick Mismetti (FR)

08:30 - 09:00

Obesity, metabolic syndrome and venous tromboembolism

Marie-Christine Alessi (FR)

09:00 - 09:30


Haemorrhagic disorders
Room A/B

Controversies in haemophilia treatment

Chairpersons: P. Lollar (US), C. Négrier (FR)

Gene transfer for inherited bleeding disorders

Katherine High (US)

08:00 - 08:30

Improved therapeutic agents for haemophilia

 

Pete Lollar (US)

08:30 - 09:00

Plasma-derived versus recombinant products
 for haemophilia treatment?

Jenny Goudemand (FR)

09:00 - 09:30


Thrombotic disorders
Room C

Methodological issues: study design and drug safety

Chairpersons: A. Leizorovicz (FR), B. L. Davidson (US)

Study design, level of evidence and guidelines

Holger J. Schuenemann (IT)
08:00 - 08:30
Risk management in the development of new antithrombotic drugs  

Alain Leizorovicz (FR)

08:30 - 09:00
Low-molecular-weight heparin in the elderly with impaired renal function  

Wendy Lim (CA)

09:00 - 09:30


Fibronolysis and fibrinogen
Room D

The fibrinolytic system and cell surface proteolysis

Chairpersons: F. Blasi (IT), B. Binder (AT)

Annexin II and fibrinolysis

Katherine Hajjar (US)
08:00 - 08:30
Cell biology of the u-PA receptor  

Francesco Blasi (IT)

08:30 - 09:00
Structure of u-PA / u-PA receptor complex  
Mingdong Huang (CN)
09:00 - 09:30

Coagulation factors and inhibitors
Room Cervin

New Roles for old coagulation factors

Chairpersons: K. T. Preissner (DE), M. M. Levi (NL)

Novel functions of protein S

Tilman Hackeng (NL)
08:00 - 08:30
Role of Factor XII in thrombosis and inflammation  

Thomas Renné (DE)

08:30 - 09:00
Factor VII activating protease (FSAP)  
Klaus T. Preissner (DE)
09:00 - 09:30

Platelets
Room Mont Blanc

Platelet-pathogen interactions

Chairpersons: E. Cramer-Bordé (FR), B. E. Kehrel (DE)

Platelets and bacteria

Dermot Cox (IE)
08:00 - 08:30
Platelets and viruses  
Elisabeth Cramer-Bordé (FR)
08:30 - 09:00
Platelets and innate immunity  
John Freedman (CA)
09:00 - 09:30

Vascular biology
Room Salève

Endothelial precursor cells

Chairpersons: F. Dignat-George (FR), A. D. Blann (UK)

Haematopoietic stem cells localization in the embryonic vessel wall

Elaine Dzierzak (NL)
08:00 - 08:30
Endothelial progenitors and circulating endothelial cells: regeneration versus degeneration
Françoise Dignat-George (FR)
08:30 - 09:00
Circulating endothelial progenitors in ischemic heart  
Douglas Losordo (US)
09:00 - 09:30

Haemorrhagic disorders
Room Jura

Haemostasis and surgery

Chairpersons: C.M. Samama (FR),  W. Korte (CH)

Antithrombotic therapy and surgery

Charles Marc Samama (FR)
08:00 - 08:30
Massive transfusion and coagulopathy:  pathophysiology and management
Yves Ozier (FR)
08:30 - 09:00
Treatment of life threatening bleeding  
Donat Spahn (CH)
09:00 - 09:30

Plenary Lectures
12:00 - 13:00

Platelets
Plenary Hall

The Marion J. Barnhart Memorial Lecture

Chairpersons: D. Meyer (FR), K. J. Clemetson (CH)

From megakaryocytes to the platelet

John Hartwig (US)
12:00 - 12:30

Haemorrhagic disorders
Plenary Hall

The Kenneth M. Brinkhous Memorial Lecture (Endowed by Wyeth)

Chairpersons: G. C. White (US), P. de Moerloose (CH)

Von Willebrand disease type 1

Ian Peake (UK)
12:30 - 13:00

State-of-the-Art -Lectures
14:15 - 15:15

Thrombotic disorders
Plenary Hall

Chairpersons: R. Verhaeghe (BE), D. Hayoz (CH)

Drug-eluting stents: trading thrombosis for restenosis?

Eric van Belle (FR)
14:15 - 14:45

Chairpersons: M. M. Samama (FR), A. S. Gallus (AU)

Past and future of genetic research in thrombosis  
Pieter H. Reitsma (NL)
14:45 - 15:15

Haemorrhagic disorders
Room A/B

Chairpersons: H. Weiss (US), C. Balduini (IT)

Approach to the diagnosis and management of mild bleeding disorders

Michael Greaves (UK)
14:15 - 14:45
Chairpersons: W. Ageno (IT), A. Batorova (SK)  
How to estimate bleeding risk in mild bleeding disorders?
Francesco Rodeghiero (IT)

14:45 - 15:15

Coagulation factors and inhibitors
Room C

The Pia Glas - Greenwalt Memorial Lecture

Chairpersons: N. A. Booth (UK), W. Ruf (US)

Activated Protein C

John Griffin (US)
14:15 - 14:45
Chairpersons: P. E. Bock (US), M. C. Guillin (FR)  
Thrombin allostery

Enrico Di Cera (US)

14:45 - 15:15

Platelets
Room Cervin / Mont Blanc

Chairpersons: J. E. Italiano (US), C. Ward (AU)

From stem cell to megakaryocyte

William Vainchenker (FR)
14:15 - 14:45

Vascular Biology
Room Cervin / Mont Blanc

Chairpersons: V. van Hinsbergh (NL), C. Ruegg (CH)

Endothelial cell heterogeneity and thrombosis

William Aird (US)
14:45 - 15:15

Monday, 9 July 2007

Symposia
08:00 - 09:30

Thrombotic disorders
Plenary Hall

Risk stratification and outcome in venous tromboembolism

Chairpersons: S. Z. Goldhaber (US), G. C. Agnelli (IT)

Long-term outcome after deep vein thrombosis

Susan Kahn (CA)

08:00 - 08:30

Risk stratification in acute pulmonary embolism: how and what for?

Samuel Z. Goldhaber (US)

08:30 - 09:00

Long-term prognosis of pulmonary embolism

Guy Meyer (FR)

09:00 - 09:30


Haemorrhagic disorders
Room A/B

Haemophilia inhibitors

Chairpersons: J. M. Saint-Rémy (BE), G. Dolan (UK)

Anti-idiotypic monoclonal antibodies for treatment of factor VIII inhibitors

Jean-Marie Saint-Rémy (BE)

08:00 - 08:30

Genetic and environmental risk factors for FVIII inhibitor development

 

Jan Astermark (SE)

08:30 - 09:00

Rituximab in the treatment of FVIII inhibitors
Cindy Leissinger (US)
09:00 - 09:30

Haemorrhagic disorders
Room C

Rare bleeding disorders

Chairpersons: A. Zivelin (IL), C. Lee (UK)

What do we expect from the International Registry?

Flora Peyvandi (IT)

08:00 - 08:30

Clinical phenotypes and factor VII genotype in
congenital factor VII deficiency

 

Jean-François Schved (FR)

08:30 - 09:00

Factor XI phenotype-genotype correlations
Ariella Zivelin (IL)

09:00 - 09:30


Fibronolysis and fibrinogen
Room D

Fibrinolysis and the central nervous system

Chairpersons: D. Lawrence (US), D. Collen (BE)

Regulation of plasminogen activator activation in the central nervous system

Daniel Lawrence (US)
08:00 - 08:30
The role of t-PA in the nervous system  

Sidney Stricklandor (US)

08:30 - 09:00
Plasminogen activators and proteases in stroke  
Gregory Del Zoppo (US)
09:00 - 09:30

Coagulation factors and inhibitors
Room Cervin

Protein C

Chairpersons: B. Dahlbäck (SE), D. Lane (UK)

Protein C pathway

Björn Dahlbäck (SE)
08:00 - 08:30
Endothelial protein C receptor  

Charles Esmon (US)

08:30 - 09:00
Cellular functions of APC  
Matthias Riewald (US)
09:00 - 09:30

Platelets
Room Mont Blanc

Platelet signaling mechanisms

Chairpersons: S. Watson (UK), R. R. Montgomery (US)

Contact-dependent interactions that affect thrombus growth and stability

Laurence F. Brass (US)
08:00 - 08:30
NO/cGMP and ROS regulatory pathways  
Ulrich Walter (DE)
08:30 - 09:00
Novel platelet membrane receptors and signaling proteins  
Steve Watson (UK)
09:00 - 09:30

Vascular biology
Room Salève

Models of arterial and venous thrombosis

Chairpersons: B. C. Furie (US), G. J. Johnson (US)

In vivo monitoring of thrombus formation

Barbara C. Furie (US)
08:00 - 08:30
Platelets and leukocyte interaction with the vessel wall
Denisa Wagner (US)
08:30 - 09:00
Thrombomodulin - guarding the vascular endothelium  
Edward M. Conway (BE)
09:00 - 09:30

Innovation and technology
Room Jura

New cellular imaging approaches

Chairpersons: S. Jackson (AU), W. Ouwehand (UK)

Visual approach to proteomics

Wolfgang Baumeister (DE)
08:00 - 08:30
Structural biology of cellular machines
Wah Chiu (US)
08:30 - 09:00
New insights into the dynamics of platelet adhesion  
Shaun Jackson (AU)
09:00 - 09:30

Plenary Lectures
12:00 - 13:00

Vascular biology
Plenary Hall

The Wright - Schulte Memorial Lecture

Chairpersons: C. Ruegg (CH), F. R. Rosendaal (NL)

Cell matrix adhesion in vascular development

Richard Hynes (US)
12:00 - 12:30

Innovation and technology
Plenary Hall

A lecture endowed by The Désiré Collen Foundation

Chairpersons: J. M. Freyssinet (FR), C. Chesterman (AU)

Thrombus formation in vivo

Bruce Furie (US)
12:30 - 13:00

State-of-the-Art -Lectures
14:15 - 15:15

Thrombotic disorders
Plenary Hall

Chairpersons: J. N. Fiessinger (FR), A. Perrier (CH)

Venous and arterial thrombosis: is there a link?

Paolo Prandoni (IT)
14:15 - 14:45

Chairpersons: A. K. Kakkar (UK), C. W. Francis (US)

Cancer and thrombosis: from the molecular mechanisms to the clinical presentations  
Harry Büller (NL)
14:45 - 15:15

Haemorrhagic disorders
Room A/B

Chairpersons: E. Berntorp (SE), R. d'Oiron (FR)

Immune tolerance for Factor VIII inhibitors in haemophilia A: current strategies and future directions

Donna Di Michele (US)
14:15 - 14:45

Coagulation factors and inhibitors
Room A/B

Chairpersons: M. Schapira (CH), J. Rosing (NL)

 Exosites in the specificity of blood coagulation reactions

 Paul E. Bock (US)

14:45 - 15:15


Platelets
Room C

Chairpersons: A. Nurden (FR), D.R. Phillips (US)

Programmed autologous cleavage of platelet receptors

Michael C. Berndt (AU)
14:15 - 15:15

Innovation and technology
Room C

Chairpersons: P. de Groot (NL), A. Greinacher (DE)

Vascular proteomics

Jan Schnitzer (US)
14:45 - 15:15

Fibrinolysis and fibrinogen
Room Cervin / Mont Blanc

Chairpersons: O. Matsuo (JP), D.C. Rijken (NL)

Structure of fibrin: impact on clot stability

John Weisel (US)
14:15 - 14:45

Vascular Biology
Room Cervin / Mont Blanc

Chairpersons: G. D. Lowe (UK), B. Imhof (CH)

Plaque progression and regression in atherothrombosis

Juan J. Badimon (US)
14:45 - 15:15

Tuesday, 10 July 2007

Presidential Symposia
10:00 - 13:00

Thrombotic disorders
Plenary Hall

Chairpersons: H. Bounameaux (CH), P. M. Mannucci (IT)

Integrated diagnostic strategy for venous thromboembolism

Philip S. Wells (CA)

10:00 - 10:40

Distal DVT: worth diagnosing? Yes

Sebastian Schellong (DE)

10:40 - 11:00

Distal DVT: worth diagnosing? No

Marc Righini (CH)

11:00 - 11:20
 

Chairpersons: H. Bounameaux (CH), F. Bachmann (CH)

FXa or thrombin: is Xa a better target?

Jack Ansell (US)

11:20 - 11:40

FXa or thrombin: is thrombin a better target?

Jeffrey Weitz (CA)

11:40 - 12:00

Thrombosis and bleeding disorders outside the Western countries

The Duckert - Koller - Lüscher Memorial Lecture

 
Pier M. Mannucci (IT)
12:00 - 12:40

State-of-the-Art -Lectures
14:15 - 15:15

Thrombotic disorders
Room A

Chairpersons: M. H. Prins (NL), G. De Gaetano (IT)

Combined antiplatelet and anticoagulant therapy: clinical benefits, risks and costs

John Eikelboom (CA)
14:15 - 14:45

Chairpersons: J. Emmerich (FR), T. Brighton (AU)

Thrombosis in the elderly: specific issues  
Frits Rosendaal (NL)
14:45 - 15:15

Haemorrhagic disorders
Room B

Chairpersons: H. Salem (AU), J. F. Schved (FR)

Investigation and treatment of menorrhagia

Peter Kouides (US)
14:15 - 14:45

Coagulation factors and inhibitors
Room B

Chairpersons: D. M. Monroe (US), P. M. Sandset (NO)

 The central role of thrombin in haemostasis

 David Lane (UK)

14:45 - 15:15


Platelets
Room C

Chairpersons: M. Hoylaerts (BE), C. Mannhalter (AT)

Models to evaluate antiplatelet agents

Peter J. Newman (US)
14:15 - 14:45

Innovation and technology
Room C

Chairpersons: D. Fitzgerald (IE), U. Walter (DE)

Platelet genomics and the risk of atherothrombosis

Willem Ouwehand (UK)
14:45 - 15:15

Fibrinolysis and fibrinogen
Room Cervin / Mont Blanc

Chairpersons: S. Lord (US), H. R. Lijnen (BE)

Congenital disorders of fibrinogen

Marguerite Neerman-Arbez (CH)
14:15 - 14:45

Vascular Biology
Room Cervin / Mont Blanc

Chairpersons: J. H. Mc Vey (UK), D. D. Wagner (US)

Zebrafish: from haematology to hydrology

Pudur Jagadeeswaran (US)
14:45 - 15:15

Wednesday, 11 July 2007

Symposia
08:00 - 09:30

Thrombotic disorders
Plenary Hall

Treatment of venous tromboembolism: controversies

Chairpersons: S. Schulman (CA), H. Décousus (FR)

Risk stratification of venous tromboembolism recurrence

Marc Rodger (CA)

08:00 - 08:30

Optimal duration of anticoagulant treatment in patients with venous tromboembolism

Giancarlo Agnelli (IT)

08:30 - 09:00

Treatment of antiphospholipid syndrome

Sam Schulman (CA)

09:00 - 09:30


Haemorrhagic disorders
Room A/B

Current and future assays of haemostasis

Chairpersons: M. Shima (JP), M. Greaves (UK)

Global assay using clot waveform and thrombin generation assays

Midori Shima (JP)

08:00 - 08:30

Monitoring haemostatic response using dynamic fibrin generation methods

 

Benny Sorensen (DK)

08:30 - 09:00

Global assays of platelet function in diagnostic testing
Catherine Hayward (CA)

09:00 - 09:30


Platelets
Room C

Platelet disorders: clinical aspects

Chairpersons: A. Goodall (UK), M. Cattaneo (IT)

Clinical approach to heparin-induced thrombocytopenia

Lorenzo Alberio (CH)
08:00 - 08:30
Giant platelet syndromes  
Carlo L. Balduini (IT)
08:30 - 09:00
The spectrum of the platelet response  
Allison Goodall (UK)
09:00 - 09:30

Thrombotic disorders
Room D

Thrombosis in children

Chairpersons: M. Manco-Johnson (US), P. Monagle (AU)

Central venous line related thrombosis in children

Marilyn Manco-Johnson (US)
08:00 - 08:30
Paediatric stroke  

Fenella Kirkham (UK)

08:30 - 09:00
Management of arterial and venous thrombosis in paediatric patients  

Anthony Chan (CA)

09:00 - 09:30


Coagulation factors and inhibitors
Room Cervin

Thrombin

Chairpersons: J. A. Huntington (UK), A. Rezaie (US)

Non PAR receptors for thrombin

Raimondo De Cristofaro (IT)
08:00 - 08:30
Thrombin is a zymogen-like enzyme  

James A. Huntington (UK)

08:30 - 09:00
Protease activated receptors in health and disease  
Shaun Coughlin (US)
09:00 - 09:30

Platelets
Room Mont Blanc

Thrombotic microangiopathies and ADAMTS 13

Chairpersons: D. Motto (US), Y. Fujimura (JP)

Clinical aspects of hereditary and acquired thrombotic thrombocytopenic purpura

Johanna Kremer Hovinga (CH)
08:00 - 08:30
RADAMTS 13 structure and function  

Kenji Soejima (JP)

08:30 - 09:00
Mouse model of hereditary thrombotic thrombocytopenic purpura  
David Motto (US)
09:00 - 09:30

Vascular biology
Room Salève

Microparticles

Chairpersons: N. Mackman (US), A. Sturk (NL)

Clinical significance of microparticles

Ingrid Pabinger (AT)
08:00 - 08:30
Role of platelet microparticles in cancer and angiogenesis
David Varon (IL)
08:30 - 09:00
Tissue factor and microparticles  
Nigel Mackman (US)
09:00 - 09:30

Innovation and technology
Room Jura

The VWF-GPIb axis

Chairpersons: J. E. Sadler (US), J. Lopez (US)

The VWF-GPIb axis as a therapeutic target

Hans Deckmyn (BE)
08:00 - 08:30
The function of GPIb
Zaverio Ruggeri (US)
08:30 - 09:00
The function of Von Willebrand factor  
J. Evan Sadler (US)
09:00 - 09:30

Plenary Lectures
12:00 - 13:00

Fibrinolysis and fibrinogen
Plenary Hell

The Sol Sherry Memorial Lecture

Chairpersons: K. A. Bauer (US), E. K. O. Kruithof (CH)

Fibrin and fibrinolysis in infection and host defence

Jay Degen (US)
12:00 - 12:30

Coagulation factors
Plenary Hell

The  Shirley Johnson Memorial Lecture

Chairpersons: B. Lämmle (CH), B. C. Furie (US)

VKORC1, the molecular target of coumarins

Johannes Oldenburg (DE)
12:30 - 13:00

State-of-the-Art -Lectures
14:15 - 15:15

Thrombotic disorders
Plenary Hall

Chairpersons: B. Brenner (IL), J. Conard (FR)

Thrombophilia and pregnancy complications: causation or association?

Saskia Middeldorp (NL)
14:15 - 14:45

Chairpersons: P. Gaussem (FR), J.H. Beer (CH)

Antiplatelet drug resistance: molecular mechanisms and laboratory detection  
Marco Cattaneo (IT)
14:45 - 15:15

Haemorrhagic disorders
Room A/B

Chairpersons: I. Peake (UK), U. Seligsohn (IL)

Phenotype heterogeneity of severe haemophilia

Marijke Van den Berg (NL)
14:15 - 14:45

Coagulation factors and inhibitors
Room A/B
Chairpersons: G. A. Marbet (CH), C. T. Esmon (US)  
SERPINs in haemostasis, thrombosis and fibrinolysis

Frank C. Church (US)

14:45 - 15:15

Platelets
Room C

Chairpersons: A. Gallino (CH), C. Weber (DE)

Platelets, inflammation and atherosclerosis

Meinrad Gawaz (DE)
14:15 - 14:45

Chairpersons: D. K. Newman (US), J. W. Heemskerk (NL)

Platelet receptor crosstalk in collagen-induced activation of platelets

Richard Farndale (UK)
14:45 - 15:15

Fibrinolysis and fibrinogen
Room Cervin / Mont Blanc

Chairpersons: I. Juhan-Vague (FR), D. Ginsburg (US)

Regulation of plasminogen activation

Robert Medcalf (AU)
14:15 - 14:45

Vascular Biology
Room Cervin / Mont Blanc

Chairpersons: R. De Caterina (IT), Y. Ikeda (JP)

Endothelial progenitor cells

Jeremy Pearson (UK)
14:45 - 15:15